Type 2 Diabetes: The End of the Road For Pre-Diabetes

Type 2 diabetes isn't a disease like the measles. It doesn't pop up overnight. You won't wake up in the morning suddenly overtaken by an illness like a bolt out of the blue.

By the time you have discovered that you have type 2 diabetes, insulin resistance will have been an ongoing problem for quite some time.

Many type 2 diabetics may feel like they're dealing with a sudden and unanticipated development, if they aren't familiar with the dynamics of insulin resistance. But for those who recognize the road signs, the symptoms of insulin resistance have been sounding the alarm, warning of danger ahead.

Insulin resistance is the result of the body's inability to respond in a healthy manner to the hormone insulin. This poses serious problems because insulin is a major player as a hormone that regulates blood sugar (glucose) levels in the bloodstream.

When insulin can't do its job, too much glucose is in your blood, and your body ends up starved for energy. The overload of glucose goes into storage in the form of fat you really don't want.

If things continue in this unhealthy direction, the undesired and possibly unexpected destination may well be type 2 diabetes.

But it really should not come as a surprise, if you know how to read the signs. If you've been carrying extra weight, especially around the midsection, you are on the road that leads to type 2 diabetes. If others in your family have type 2 diabetes, be on the alert. You may have a genetic predisposition working against you, and you may be camping out in the outskirts of pre-diabetes.

According to the American Diabetes Association, pre-diabetes is marked by fasting blood glucose levels that fall between 100 and 125 mg/dl. Higher blood glucose levels indicate that you have arrived. You now have type 2 diabetes.

When fasting blood glucose levels hit 126 mg/dl or beyond, your pancreas is in danger of beta cell damage. Insulin secretion decreases due to toxicity of the beta cells and the cells experience apoptosis (type of cell death).

Fortunately, being pre-diabetic does not mean that developing type 2 diabetes is inevitable. Lifestyle changes such as a regular exercise regimen and healthy diet can help change your direction and put you on a better road.



Progression of Type 2 Diabetes

Moriuchi T et al, "Diabetes progression from 'high-normal' glucose in school teachers", Internal Medicine 2010;49:1271-76

Insulin Resistance: What You Don't Know Can Make You Sick

Insulin Resistance Syndrome

Insulin Resistance and Pre-diabetes



Tags: type 2,insulin resistance,blood sugar levels,blood glucose levels,pre-diabetes

Category: Causes,Overview,Type 2 Diabetes