Type 2 Diabetes May Be Linked With Alzheimer's And Other Types Of Dementia

A possible correlation between type 2 diabetes and Alzheimer's disease may exist, according to an April 6, 2011 article on Dr. Oz' website.

In people with type 2 diabetes, the pancreas has been manufacturing more insulin than normal because the insulin no longer is able to do its job. As the amount of insulin in the bloodstream climbs, it has the potential to cause harm to the brain's small blood vessels and circulation in the brain can suffer.

Insulin plays an important role in the brain. It enables the cells of the brain to receive glucose and use it to create energy, as well as in the creation of neurotransmitters. Neurotransmitters are chemicals which enable neurons (nerve cells) to talk to each other. Insulin is integral to the creation and retention of new memories and is vital to the ability to learn.

It appears that insulin is not only manufactured in the pancreas, it's also created in the brain.

Research indicates that people with diabetes are at least twice as likely to end up with Alzheimer's. According to the article on DoctorOz.com, it appears that nitrosamines may be a significant factor in developing both type 2 diabetes and Alzheimer's disease.

This seems to be a consequence of the use of nitrites for preserving food. The conversion path here is from nitrates to nitrites and then to nitrosamines in your body.Nitrosamines are potential carcinogens. Research suggests that nitrosamine contamination may lead to dementia, diabetes, obesity and fatty liver disease.

Msnbc reported on research that was published in the journal of neurology concerning a possible link between type 2 diabetes and Alzheimer's disease. In Japan, doctors followed volunteers 60 years of age or older for 11 years.

Of the group of participants, 150 had type 2 diabetes when the study began. Over time, 41 of those people later developed Alzheimer's disease. There were 559 participants who did not have type 2 diabetes. Of this group, 115 later developed dementia. The people who had the worst diabetes symptoms were seen to have three times the risk of developing dementia.

A pilot study from the Veteran's Affairs Puget Sound Health Care System in Seattle seemed to indicate that inhalation of insulin may slow down the development of Alzheimer's disease. This research is only in its infancy stage, however, and much more study is required.

In the meantime, people with diabetes, or who are at high risk for type 2 diabetes, would do well to stay with what is already used successfully as deterrents. Lifestyle changes like being more physically active and attaining and maintaining a healthy weight can reduce the risk for type 2 diabetes, and possibly for dementia as well.



Alzheimer's: Diabetes of the Brain? Pg. 1. April 6, 2011. Retrieved Dec. 1, 2011.


Alzheimer's: Diabetes of the Brain? Pg. 2. April 6, 2011. Retrieved Dec. 1, 2011.


Alzheimer's: Diabetes of the Brain? Pg. 3. April 6, 2011. Retrieved Dec. 1, 2011.


Memory Loss? Control Your Blood Sugar. Aug. 25, 2010. Retrieved Dec. 1, 2011.


Alzheimer's link yet another reason to fear diabetes. Sept. 19, 2011. Retrieved Dec. 1, 2011.


Insulin nasal spray may slow Alzheimer's. Msnbc.msn.com. Sept. 12, 2011. Retrieved Dec. 1, 2011.


Tags: diabetes,Type 2 diabetes,Alzheimers disease,dementia,risk factors,Link between Type 2 and Alzheimers

Category: Risks,Overview